The Role of Protein-Ligand Contacts in Allosteric Regulation of the Escherichia coli Catabolite Activator Protein

Allostery is a fundamental process by which ligand binding to a protein alters its activity at a distant site. Both experimental and theoretical evidence demonstrate that allostery can be communicated through altered slow relaxation protein dynamics without conformational change. The catabolite acti...

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Detalles Bibliográficos
Autores principales: Townsend, Philip D., Rodgers, Thomas L., Glover, Laura C., Korhonen, Heidi J., Richards, Shane A., Colwell, Lucy J., Pohl, Ehmke, Wilson, Mark R., Hodgson, David R. W., McLeish, Tom C. B., Cann, Martin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2015
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571973/
https://www.ncbi.nlm.nih.gov/pubmed/26187469
http://dx.doi.org/10.1074/jbc.M115.669267

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