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Molecular Dynamics Approach in the Comparison of Wild-Type and Mutant Paraoxonase-1 Apoenzyme Form

There is some evidence linking the mammalian paraoxonase-1 (PON1) loops (L1 and L2) to an increased flexibility and reactivity of its active site with potential substrates. The aim of this work is to study the structural, dynamical, and functional effects of the most flexible regions close to the ac...

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Detalles Bibliográficos
Autores principales: Amine, Khadija, Miri, Lamia, Naimi, Adil, Saile, Rachid, El Kharrim, Abderrahmane, Mikou, Afaf, Kettani, Anass
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571988/
https://www.ncbi.nlm.nih.gov/pubmed/26417201
http://dx.doi.org/10.4137/BBI.S25626

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