Clinical and In Vitro Studies on Impact of High-Dose Etoposide Pharmacokinetics Prior Allogeneic Hematopoietic Stem Cell Transplantation for Childhood Acute Lymphoblastic Leukemia on the Risk of Post-Transplant Leukemia Relapse

The impact of etoposide (VP-16) plasma concentrations on the day of allogeneic hematopoietic stem cell transplantation (allo-HSCT) on leukemia-free survival in children with acute lymphoblastic leukemia (ALL) was studied. In addition, the in vitro effects of VP-16 on the lymphocytes proliferation, c...

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Detalles Bibliográficos
Autores principales: Sobiak, Joanna, Kazimierczak, Urszula, Kowalczyk, Dariusz W., Chrzanowska, Maria, Styczyński, Jan, Wysocki, Mariusz, Szpecht, Dawid, Wachowiak, Jacek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Basel 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4572077/
https://www.ncbi.nlm.nih.gov/pubmed/26040247
http://dx.doi.org/10.1007/s00005-015-0343-0

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