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The diabetes gene Zfp69 modulates hepatic insulin sensitivity in mice

AIMS/HYPOTHESIS: Zfp69 was previously identified by positional cloning as a candidate gene for obesity-associated diabetes. C57BL/6J and New Zealand obese (NZO) mice carry a loss-of-function mutation due to the integration of a retrotransposon. On the NZO background, the Zfp69 locus caused severe hy...

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Detalles Bibliográficos
Autores principales: Chung, Bomee, Stadion, Mandy, Schulz, Nadja, Jain, Deepak, Scherneck, Stephan, Joost, Hans-Georg, Schürmann, Annette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4572078/
https://www.ncbi.nlm.nih.gov/pubmed/26232096
http://dx.doi.org/10.1007/s00125-015-3703-8