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The Independent Probabilistic Firing of Transcription Factors: A Paradigm for Clonal Variability in the Zebrafish Retina
Early retinal progenitor cells (RPCs) in vertebrates produce lineages that vary greatly both in terms of cell number and fate composition, yet how this variability is achieved remains unknown. One possibility is that these RPCs are individually distinct and that each gives rise to a unique lineage....
Autores principales: | Boije, Henrik, Rulands, Steffen, Dudczig, Stefanie, Simons, Benjamin D., Harris, William A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4572358/ https://www.ncbi.nlm.nih.gov/pubmed/26343455 http://dx.doi.org/10.1016/j.devcel.2015.08.011 |
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