First effects of rising amyloid-β in transgenic mouse brain: synaptic transmission and gene expression

Detecting and treating Alzheimer’s disease, before cognitive deficits occur, has become the health challenge of our time. The earliest known event in Alzheimer’s disease is rising amyloid-β. Previous studies have suggested that effects on synaptic transmission may precede plaque deposition. Here we...

Descripción completa

Detalles Bibliográficos
Autores principales: Cummings, Damian M., Liu, Wenfei, Portelius, Erik, Bayram, Sevinç, Yasvoina, Marina, Ho, Sui-Hin, Smits, Hélène, Ali, Shabinah S., Steinberg, Rivka, Pegasiou, Chrysia-Maria, James, Owain T., Matarin, Mar, Richardson, Jill C., Zetterberg, Henrik, Blennow, Kaj, Hardy, John A., Salih, Dervis A., Edwards, Frances A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4572488/
https://www.ncbi.nlm.nih.gov/pubmed/25981962
http://dx.doi.org/10.1093/brain/awv127

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4572488/
https://www.ncbi.nlm.nih.gov/pubmed/25981962
http://dx.doi.org/10.1093/brain/awv127

Ejemplares similares