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Targeting stem cell niche can protect hematopoietic stem cells from chemotherapy and G-CSF treatment
INTRODUCTION: Hematopoietic stem/progenitor cells (HSPCs) reside in a tightly controlled local microenvironment called bone marrow niche. The specialized microenvironment or niche not only provides a favorable habitat for HSPC maintenance and development but also governs stem cell function. METHOD:...
Autores principales: | Li, Sidan, Zou, Dehui, Li, Changhong, Meng, Hengxing, Sui, Weiwei, Feng, Sizhou, Cheng, Tao, Zhai, Qiongli, Qiu, Lugui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4572669/ https://www.ncbi.nlm.nih.gov/pubmed/26373707 http://dx.doi.org/10.1186/s13287-015-0164-4 |
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