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DNA Damage Response Checkpoint Activation Drives KP1019 Dependent Pre-Anaphase Cell Cycle Delay in S. cerevisiae

Careful regulation of the cell cycle is required for proper replication, cell division, and DNA repair. DNA damage–including that induced by many anticancer drugs–results in cell cycle delay or arrest, which can allow time for repair of DNA lesions. Although its molecular mechanism of action remains...

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Detalles Bibliográficos
Autores principales: Bierle, Lindsey A., Reich, Kira L., Taylor, Braden E., Blatt, Eliot B., Middleton, Sydney M., Burke, Shawnecca D., Stultz, Laura K., Hanson, Pamela K., Partridge, Janet F., Miller, Mary E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4572706/
https://www.ncbi.nlm.nih.gov/pubmed/26375390
http://dx.doi.org/10.1371/journal.pone.0138085