REDD2-mediated inhibition of mTOR promotes dendrite retraction induced by axonal injury

Dendritic defects occur in neurodegenerative diseases accompanied by axonopathy, yet the mechanisms that regulate these pathologic changes are poorly understood. Using Thy1-YFPH mice subjected to optic nerve axotomy, we demonstrate early retraction of retinal ganglion cell (RGC) dendrites and select...

Descripción completa

Detalles Bibliográficos
Autores principales: Morquette, B, Morquette, P, Agostinone, J, Feinstein, E, McKinney, R A, Kolta, A, Di Polo, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4572858/
https://www.ncbi.nlm.nih.gov/pubmed/25257176
http://dx.doi.org/10.1038/cdd.2014.149

Ejemplares similares

Ejemplares similares