Glucocorticoids promote structural and functional maturation of foetal cardiomyocytes: a role for PGC-1α

Glucocorticoid levels rise dramatically in late gestation to mature foetal organs in readiness for postnatal life. Immature heart function may compromise survival. Cardiomyocyte glucocorticoid receptor (GR) is required for the structural and functional maturation of the foetal heart in vivo, yet the...

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Detalles Bibliográficos
Autores principales: Rog-Zielinska, E A, Craig, M-A, Manning, J R, Richardson, R V, Gowans, G J, Dunbar, D R, Gharbi, K, Kenyon, C J, Holmes, M C, Hardie, D G, Smith, G L, Chapman, K E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4572859/
https://www.ncbi.nlm.nih.gov/pubmed/25361084
http://dx.doi.org/10.1038/cdd.2014.181

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