Conditional deletion of nonmuscle myosin II-A in mouse tongue epithelium results in squamous cell carcinoma

To investigate the contribution of nonmuscle myosin II-A (NM II-A) to early cardiac development we crossed Myh9 floxed mice and Nkx2.5 cre-recombinase mice. Nkx2.5 is expressed in the early heart (E7.5) and later in the tongue epithelium. Mice homozygous for deletion of NM II-A (A(Nkx)/A(Nkx)) are b...

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Autores principales: Anne Conti, Mary, Saleh, Anthony D., Brinster, Lauren R., Cheng, Hui, Chen, Zhong, Cornelius, Shaleeka, Liu, Chengyu, Ma, Xuefei, Van Waes, Carter, Adelstein, Robert S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4572924/
https://www.ncbi.nlm.nih.gov/pubmed/26369831
http://dx.doi.org/10.1038/srep14068

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