Cargando…
Respiratory muscle training with normocapnic hyperpnea improves ventilatory pattern and thoracoabdominal coordination, and reduces oxygen desaturation during endurance exercise testing in COPD patients
BACKGROUND: Few data are available about the effects of respiratory muscle training with normocapnic hyperpnea (NH) in COPD. The aim is to evaluate the effects of 4 weeks of NH (Spirotiger(®)) on ventilatory pattern, exercise capacity, and quality of life (QoL) in COPD patients. METHODS: Twenty-six...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573075/ https://www.ncbi.nlm.nih.gov/pubmed/26392764 http://dx.doi.org/10.2147/COPD.S88609 |
_version_ | 1782390450781421568 |
---|---|
author | Bernardi, Eva Pomidori, Luca Bassal, Faisy Contoli, Marco Cogo, Annalisa |
author_facet | Bernardi, Eva Pomidori, Luca Bassal, Faisy Contoli, Marco Cogo, Annalisa |
author_sort | Bernardi, Eva |
collection | PubMed |
description | BACKGROUND: Few data are available about the effects of respiratory muscle training with normocapnic hyperpnea (NH) in COPD. The aim is to evaluate the effects of 4 weeks of NH (Spirotiger(®)) on ventilatory pattern, exercise capacity, and quality of life (QoL) in COPD patients. METHODS: Twenty-six COPD patients (three females), ages 49–82 years, were included in this study. Spirometry and maximal inspiratory pressure, St George Respiratory Questionnaire, 6-minute walk test, and symptom-limited endurance exercise test (endurance test to the limit of tolerance [tLim]) at 75%–80% of peak work rate up to a Borg Score of 8–9/10 were performed before and after NH. Patients were equipped with ambulatory inductive plethysmography (LifeShirt(®)) to evaluate ventilatory pattern and thoracoabdominal coordination (phase angle [PhA]) during tLim. After four supervised sessions, subjects trained at home for 4 weeks – 10 minutes twice a day at 50% of maximal voluntary ventilation. The workload was adjusted during the training period to maintain a Borg Score of 5–6/10. RESULTS: Twenty subjects completed the study. After NH, maximal inspiratory pressure significantly increased (81.5±31.6 vs 91.8±30.6 cmH(2)O, P<0.01); exercise endurance time (+150 seconds, P=0.04), 6-minute walk test (+30 meters, P=0.03), and QoL (−8, P<0.01) all increased. During tLim, the ventilatory pattern changed significantly (lower ventilation, lower respiratory rate, higher tidal volume); oxygen desaturation, PhA, and dyspnea Borg Score were lower for the same work intensity (P<0.01, P=0.02, and P<0.01, respectively; one-way ANOVA). The improvement in tidal volume and oxygen saturation after NH were significantly related (R(2)=0.65, P<0.01). CONCLUSION: As expected, NH improves inspiratory muscle performance, exercise capacity, and QoL. New results are significant change in ventilatory pattern, which improves oxygen saturation, and an improvement in thoracoabdominal coordination (lower PhA). These two facts could explain the reduced dyspnea during the endurance test. All these results together may play a role in improving exercise capacity after NH training. |
format | Online Article Text |
id | pubmed-4573075 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Dove Medical Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-45730752015-09-21 Respiratory muscle training with normocapnic hyperpnea improves ventilatory pattern and thoracoabdominal coordination, and reduces oxygen desaturation during endurance exercise testing in COPD patients Bernardi, Eva Pomidori, Luca Bassal, Faisy Contoli, Marco Cogo, Annalisa Int J Chron Obstruct Pulmon Dis Original Research BACKGROUND: Few data are available about the effects of respiratory muscle training with normocapnic hyperpnea (NH) in COPD. The aim is to evaluate the effects of 4 weeks of NH (Spirotiger(®)) on ventilatory pattern, exercise capacity, and quality of life (QoL) in COPD patients. METHODS: Twenty-six COPD patients (three females), ages 49–82 years, were included in this study. Spirometry and maximal inspiratory pressure, St George Respiratory Questionnaire, 6-minute walk test, and symptom-limited endurance exercise test (endurance test to the limit of tolerance [tLim]) at 75%–80% of peak work rate up to a Borg Score of 8–9/10 were performed before and after NH. Patients were equipped with ambulatory inductive plethysmography (LifeShirt(®)) to evaluate ventilatory pattern and thoracoabdominal coordination (phase angle [PhA]) during tLim. After four supervised sessions, subjects trained at home for 4 weeks – 10 minutes twice a day at 50% of maximal voluntary ventilation. The workload was adjusted during the training period to maintain a Borg Score of 5–6/10. RESULTS: Twenty subjects completed the study. After NH, maximal inspiratory pressure significantly increased (81.5±31.6 vs 91.8±30.6 cmH(2)O, P<0.01); exercise endurance time (+150 seconds, P=0.04), 6-minute walk test (+30 meters, P=0.03), and QoL (−8, P<0.01) all increased. During tLim, the ventilatory pattern changed significantly (lower ventilation, lower respiratory rate, higher tidal volume); oxygen desaturation, PhA, and dyspnea Borg Score were lower for the same work intensity (P<0.01, P=0.02, and P<0.01, respectively; one-way ANOVA). The improvement in tidal volume and oxygen saturation after NH were significantly related (R(2)=0.65, P<0.01). CONCLUSION: As expected, NH improves inspiratory muscle performance, exercise capacity, and QoL. New results are significant change in ventilatory pattern, which improves oxygen saturation, and an improvement in thoracoabdominal coordination (lower PhA). These two facts could explain the reduced dyspnea during the endurance test. All these results together may play a role in improving exercise capacity after NH training. Dove Medical Press 2015-09-10 /pmc/articles/PMC4573075/ /pubmed/26392764 http://dx.doi.org/10.2147/COPD.S88609 Text en © 2015 Bernardi et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. |
spellingShingle | Original Research Bernardi, Eva Pomidori, Luca Bassal, Faisy Contoli, Marco Cogo, Annalisa Respiratory muscle training with normocapnic hyperpnea improves ventilatory pattern and thoracoabdominal coordination, and reduces oxygen desaturation during endurance exercise testing in COPD patients |
title | Respiratory muscle training with normocapnic hyperpnea improves ventilatory pattern and thoracoabdominal coordination, and reduces oxygen desaturation during endurance exercise testing in COPD patients |
title_full | Respiratory muscle training with normocapnic hyperpnea improves ventilatory pattern and thoracoabdominal coordination, and reduces oxygen desaturation during endurance exercise testing in COPD patients |
title_fullStr | Respiratory muscle training with normocapnic hyperpnea improves ventilatory pattern and thoracoabdominal coordination, and reduces oxygen desaturation during endurance exercise testing in COPD patients |
title_full_unstemmed | Respiratory muscle training with normocapnic hyperpnea improves ventilatory pattern and thoracoabdominal coordination, and reduces oxygen desaturation during endurance exercise testing in COPD patients |
title_short | Respiratory muscle training with normocapnic hyperpnea improves ventilatory pattern and thoracoabdominal coordination, and reduces oxygen desaturation during endurance exercise testing in COPD patients |
title_sort | respiratory muscle training with normocapnic hyperpnea improves ventilatory pattern and thoracoabdominal coordination, and reduces oxygen desaturation during endurance exercise testing in copd patients |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573075/ https://www.ncbi.nlm.nih.gov/pubmed/26392764 http://dx.doi.org/10.2147/COPD.S88609 |
work_keys_str_mv | AT bernardieva respiratorymuscletrainingwithnormocapnichyperpneaimprovesventilatorypatternandthoracoabdominalcoordinationandreducesoxygendesaturationduringenduranceexercisetestingincopdpatients AT pomidoriluca respiratorymuscletrainingwithnormocapnichyperpneaimprovesventilatorypatternandthoracoabdominalcoordinationandreducesoxygendesaturationduringenduranceexercisetestingincopdpatients AT bassalfaisy respiratorymuscletrainingwithnormocapnichyperpneaimprovesventilatorypatternandthoracoabdominalcoordinationandreducesoxygendesaturationduringenduranceexercisetestingincopdpatients AT contolimarco respiratorymuscletrainingwithnormocapnichyperpneaimprovesventilatorypatternandthoracoabdominalcoordinationandreducesoxygendesaturationduringenduranceexercisetestingincopdpatients AT cogoannalisa respiratorymuscletrainingwithnormocapnichyperpneaimprovesventilatorypatternandthoracoabdominalcoordinationandreducesoxygendesaturationduringenduranceexercisetestingincopdpatients |