Cargando…

Hepatic but Not CNS-Expressed Human C-Reactive Protein Inhibits Experimental Autoimmune Encephalomyelitis in Transgenic Mice

We recently demonstrated that human C-reactive protein (CRP), expressed hepatically in transgenic mice (CRPtg), improved the outcome of experimental autoimmune encephalomyelitis (EAE), a murine model of multiple sclerosis (MS). The liver is the primary site of CRP synthesis in humans and in CRPtg mi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wright, Tyler T, Jimenez, Rachel V., Morgan, Todd E., Bali, Namrata, Hou, Xiaogang, McCrory, Mark A., Finch, Caleb E., Szalai, Alexander J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573232/ https://www.ncbi.nlm.nih.gov/pubmed/26421184 http://dx.doi.org/10.1155/2015/640171

Ejemplares similares

Inhibition of Experimental Autoimmune Encephalomyelitis in Human C-Reactive Protein Transgenic Mice Is FcγRIIB Dependent
por: Hu, Xian-Zhen, et al.
Publicado: (2010)

A Selective Inhibitor of Human C-reactive Protein Translation Is Efficacious In Vitro and in C-reactive Protein Transgenic Mice and Humans
por: Jones, Nicholas R, et al.
Publicado: (2012)

Clozapine reduces infiltration into the CNS by targeting migration in experimental autoimmune encephalomyelitis
por: Robichon, Katharina, et al.
Publicado: (2020)

Induction of Golli-MBP Expression in CNS Macrophages During Acute LPS-Induced CNS Inflammation and Experimental Autoimmune Encephalomyelitis (EAE)
por: Papenfuss, Tracey L., et al.
Publicado: (2007)

Matrix metalloproteinase-7 facilitates immune access to the CNS in experimental autoimmune encephalomyelitis
por: Buhler, Lillian A, et al.
Publicado: (2009)

Transgenic Interleukin 10 Prevents Induction of Experimental Autoimmune Encephalomyelitis
por: Cua, Daniel J., et al.
Publicado: (1999)

The iNOS Activity During an Immune Response Controls the CNS Pathology in Experimental Autoimmune Encephalomyelitis
por: Sonar, Sandip Ashok, et al.
Publicado: (2019)

The neonatal CNS is not conducive for encephalitogenic Th1 T cells and B cells during experimental autoimmune encephalomyelitis
por: Cravens, Petra D, et al.
Publicado: (2013)

STEAP4 expression in CNS resident cells promotes Th17 cell-induced autoimmune encephalomyelitis
por: Zhao, Junjie, et al.
Publicado: (2021)

Nogo-A antibody delivery through the olfactory mucosa mitigates experimental autoimmune encephalomyelitis in the mouse CNS
por: Pernet, Vincent, et al.
Publicado: (2023)

RGC-32 Regulates Generation of Reactive Astrocytes in Experimental Autoimmune Encephalomyelitis
por: Tatomir, Alexandru, et al.
Publicado: (2021)

C-Reactive Protein (CRP) and Autoimmune Disease: Facts and Conjectures
por: Szalai, Alexander J.
Publicado: (2004)

Kinetics of T cell response in the testes and CNS during experimental autoimmune encephalomyelitis: Simultaneous blood-brain and -testis barrier permeability?
por: Pakravan, Nafiseh, et al.
Publicado: (2019)

Microwave & Magnetic (M(2)) Proteomics Reveals CNS-Specific Protein Expression Waves that Precede Clinical Symptoms of Experimental Autoimmune Encephalomyelitis
por: Raphael, Itay, et al.
Publicado: (2014)

SIRT1 inactivation switches reactive astrocytes to an antiinflammatory phenotype in CNS autoimmunity
por: Zhang, Weifeng, et al.
Publicado: (2022)

Graphene Oxide Nanosheets Reduce Astrocyte Reactivity to Inflammation and Ameliorate Experimental Autoimmune Encephalomyelitis
por: Di Mauro, Giuseppe, et al.
Publicado: (2023)

2nd Accelerator Instrumentation Workshop
por: McCrory, Elliott S
Publicado: (1991)

Myeloid cell transmigration across the CNS vasculature triggers IL-1β–driven neuroinflammation during autoimmune encephalomyelitis in mice
por: Lévesque, Sébastien A., et al.
Publicado: (2016)

Regulation of Immune Responses and Autoimmune Encephalomyelitis by PPARs
por: Yang, Yuhong, et al.
Publicado: (2010)

Understanding Addiction as a Developmental Disorder: An Argument for a Developmentally Informed Multilevel Approach
por: McCrory, E. J., et al.
Publicado: (2015)

Treg in CNS autoimmune disease
por: Anderton, Stephen M
Publicado: (2012)

Role of Microglia in CNS Autoimmunity
por: Goldmann, Tobias, et al.
Publicado: (2013)

Of primary and secondary CNS autoimmunity
por: Dalmau, Josep
Publicado: (2018)

Impact of pregabalin treatment on synaptic plasticity and glial reactivity during the course of experimental autoimmune encephalomyelitis
por: Silva, Gleidy A A, et al.
Publicado: (2014)

Loss of the receptor tyrosine kinase Axl leads to enhanced inflammation in the CNS and delayed removal of myelin debris during Experimental Autoimmune Encephalomyelitis
por: Weinger, Jason G, et al.
Publicado: (2011)

OHE for spread prevention
por: McCrory, P. V.
Publicado: (2021)

Dynamics of B cell subsets within the CNS during viral encephalomyelitis
por: Disano, Krista, et al.
Publicado: (2014)

Amelioration of Experimental Autoimmune Encephalomyelitis by Anatabine
por: Paris, Daniel, et al.
Publicado: (2013)

Environmental Influences in Experimental Autoimmune Encephalomyelitis
por: Constantinescu, Cris S
Publicado: (2005)

Contribution of Pannexin1 to Experimental Autoimmune Encephalomyelitis
por: Lutz, Sarah E., et al.
Publicado: (2013)

Myelin-reactive antibodies initiate T cell-mediated CNS autoimmune disease by opsonization of endogenous antigen
por: Kinzel, Silke, et al.
Publicado: (2016)

PEG Minocycline-Liposomes Ameliorate CNS Autoimmune Disease
por: Hu, Wei, et al.
Publicado: (2009)

Astrocytic estrogen receptors and impaired neurotrophic responses in a rat model of perimenopause
por: Morgan, Todd E., et al.
Publicado: (2015)

Routine Rectal Biopsy?
por: Mehta, Chaitanya, et al.
Publicado: (2007)

The role of T-lymphocytes in neuropathic pain initiation, development of chronicity and treatment
por: Galvin, DA, et al.
Publicado: (2021)

Transcriptome Profiling in the Hippocampi of Mice with Experimental Autoimmune Encephalomyelitis
por: Weerasinghe-Mudiyanselage, Poornima D. E., et al.
Publicado: (2022)

Cannabidiol reduces seizures following CNS infection with Theiler's murine encephalomyelitis virus
por: Patel, Dipan C., et al.
Publicado: (2019)

Inhibiting C-Reactive Protein for the Treatment of Cardiovascular Disease: Promising Evidence from Rodent Models
por: Szalai, Alexander J., et al.
Publicado: (2014)

Neuronal microRNA regulation in Experimental Autoimmune Encephalomyelitis
por: Juźwik, Camille A., et al.
Publicado: (2018)

Correction: Contribution of Pannexin1 to Experimental Autoimmune Encephalomyelitis
por: Lutz, Sarah E., et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_u1n89fdloif97r841gd2moqtj9