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Functional Outcomes: One Year after a Cardiac Arrest

Objective. The study aim was to characterize the time-course of recovery in impairments, activity limitations, participation restrictions, disability, and quality of life during the first year after cardiac arrest. Secondarily, the study described the associations between the instruments used to mea...

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Autores principales: Raina, Ketki D., Rittenberger, Jon C., Holm, Margo B., Callaway, Clifton W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573239/
https://www.ncbi.nlm.nih.gov/pubmed/26421282
http://dx.doi.org/10.1155/2015/283608
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author Raina, Ketki D.
Rittenberger, Jon C.
Holm, Margo B.
Callaway, Clifton W.
author_facet Raina, Ketki D.
Rittenberger, Jon C.
Holm, Margo B.
Callaway, Clifton W.
author_sort Raina, Ketki D.
collection PubMed
description Objective. The study aim was to characterize the time-course of recovery in impairments, activity limitations, participation restrictions, disability, and quality of life during the first year after cardiac arrest. Secondarily, the study described the associations between the instruments used to measure each of these domains. Methods. Measures of global disability (Cerebral Performance Category, CPC, Modified Rankin Scale, mRS), quality of life, activity limitations, participation restrictions, and affective and cognitive impairments were administered to 29 participants 1, 6, and 12 months after cardiac arrest. Results. Global measures of disability indicated recovery between one month and one year after cardiac arrest (mean CPC: 2.1 versus 1.69,  P < 0.05; mean mRS: 2.55 versus 1.83, P < 0.05). While global measures of disability were moderately associated with participation, they were poorly associated with other measures. The cohort endorsed depressive symptomatology throughout the year but did not have detectable cognitive impairment. Conclusions. Recovery from cardiac arrest is multifaceted and recovery continues for months depending upon the measures being used. Measures of global disability, reintegration into the community, and quality of life yield different information. Future clinical trials should include a combination of measures to yield the most complete representation of recovery after cardiac arrest.
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spelling pubmed-45732392015-09-29 Functional Outcomes: One Year after a Cardiac Arrest Raina, Ketki D. Rittenberger, Jon C. Holm, Margo B. Callaway, Clifton W. Biomed Res Int Research Article Objective. The study aim was to characterize the time-course of recovery in impairments, activity limitations, participation restrictions, disability, and quality of life during the first year after cardiac arrest. Secondarily, the study described the associations between the instruments used to measure each of these domains. Methods. Measures of global disability (Cerebral Performance Category, CPC, Modified Rankin Scale, mRS), quality of life, activity limitations, participation restrictions, and affective and cognitive impairments were administered to 29 participants 1, 6, and 12 months after cardiac arrest. Results. Global measures of disability indicated recovery between one month and one year after cardiac arrest (mean CPC: 2.1 versus 1.69,  P < 0.05; mean mRS: 2.55 versus 1.83, P < 0.05). While global measures of disability were moderately associated with participation, they were poorly associated with other measures. The cohort endorsed depressive symptomatology throughout the year but did not have detectable cognitive impairment. Conclusions. Recovery from cardiac arrest is multifaceted and recovery continues for months depending upon the measures being used. Measures of global disability, reintegration into the community, and quality of life yield different information. Future clinical trials should include a combination of measures to yield the most complete representation of recovery after cardiac arrest. Hindawi Publishing Corporation 2015 2015-09-03 /pmc/articles/PMC4573239/ /pubmed/26421282 http://dx.doi.org/10.1155/2015/283608 Text en Copyright © 2015 Ketki D. Raina et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Raina, Ketki D.
Rittenberger, Jon C.
Holm, Margo B.
Callaway, Clifton W.
Functional Outcomes: One Year after a Cardiac Arrest
title Functional Outcomes: One Year after a Cardiac Arrest
title_full Functional Outcomes: One Year after a Cardiac Arrest
title_fullStr Functional Outcomes: One Year after a Cardiac Arrest
title_full_unstemmed Functional Outcomes: One Year after a Cardiac Arrest
title_short Functional Outcomes: One Year after a Cardiac Arrest
title_sort functional outcomes: one year after a cardiac arrest
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573239/
https://www.ncbi.nlm.nih.gov/pubmed/26421282
http://dx.doi.org/10.1155/2015/283608
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