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PKC and AKT Modulate cGMP/PKG Signaling Pathway on Platelet Aggregation in Experimental Sepsis

Sepsis severity has been positively correlated with platelet dysfunction, which may be due to elevations in nitric oxide (NO) and cGMP levels. Protein kinase C, Src kinases, PI3K and AKT modulate platelet activity in physiological conditions, but no studies evaluated the role of these enzymes in pla...

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Detalles Bibliográficos
Autores principales:	Lopes-Pires, M. Elisa, Naime, Ana C. Antunes, Almeida Cardelli, Nádia J., Anjos, Débora J., Antunes, Edson, Marcondes, Sisi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573322/ https://www.ncbi.nlm.nih.gov/pubmed/26375024 http://dx.doi.org/10.1371/journal.pone.0137901

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