Identification of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFKFB4) as a Novel Autophagy Regulator by High Content shRNA Screening

Deregulation of autophagy has been linked to multiple degenerative diseases and cancer, thus the identification of novel autophagy regulators for potential therapeutic intervention is important. To meet this need, we developed a high content image-based shRNA screen monitoring levels of the autophag...

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Detalles Bibliográficos
Autores principales: Strohecker, Anne M., Joshi, Shilpy, Possemato, Richard, Abraham, Robert T., Sabatini, David M., White, Eileen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573377/
https://www.ncbi.nlm.nih.gov/pubmed/25772235
http://dx.doi.org/10.1038/onc.2015.23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573377/
https://www.ncbi.nlm.nih.gov/pubmed/25772235
http://dx.doi.org/10.1038/onc.2015.23

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