Cargando…

Identification and characterization of [6]-shogaol from ginger as inhibitor of vascular smooth muscle cell proliferation

SCOPE: Vascular smooth muscle cell (VSMC) proliferation is involved in the pathogenesis of cardiovascular disease, making the identification of new counteracting agents and their mechanisms of action relevant. Ginger and its constituents have been reported to improve cardiovascular health, but no st...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Rongxia, Heiss, Elke H, Sider, Nadine, Schinkovitz, Andreas, Gröblacher, Barbara, Guo, Dean, Bucar, Franz, Bauer, Rudolf, Dirsch, Verena M, Atanasov, Atanas G
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Ltd 2015
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573514/ https://www.ncbi.nlm.nih.gov/pubmed/25631547 http://dx.doi.org/10.1002/mnfr.201400791

Ejemplares similares

Capsaicin from chili ( Capsicum spp.) inhibits vascular smooth muscle cell proliferation
por: Liu, Rongxia, et al.
Publicado: (2015)

6‐Dihydroparadol, a Ginger Constituent, Enhances Cholesterol Efflux from THP‐1‐Derived Macrophages
por: Wang, Dongdong, et al.
Publicado: (2018)

Nonprenylated Xanthones from Gentiana lutea, Frasera caroliniensis, and Centaurium erythraea as Novel Inhibitors of Vascular Smooth Muscle Cell Proliferation
por: Waltenberger, Birgit, et al.
Publicado: (2015)

Xanthohumol Blocks Proliferation and Migration of Vascular Smooth Muscle Cells in Vitro and Reduces Neointima Formation in Vivo
por: Liu, Rongxia, et al.
Publicado: (2017)

Resveratrol inhibits migration and Rac1 activation in EGF- but not PDGF-activated vascular smooth muscle cells
por: Kumerz, Mario, et al.
Publicado: (2011)

Plumericin inhibits proliferation of vascular smooth muscle cells by blocking STAT3 signaling via S-glutathionylation
por: Heiss, Elke H, et al.
Publicado: (2016)

Inhibition of growth factor mediated Akt phosphorylation in vascular smooth muscle cells by resveratrol: the contribution of SH2 domain containing phosphatase 2 and reactive oxygen species
por: Schreiner, Cornelia E, et al.
Publicado: (2008)

Bupleurum chinense Roots: a Bioactivity-Guided Approach toward Saponin-Type NF- κ B Inhibitors
por: Liu, Xin, et al.
Publicado: (2017)

Short Chain (≤C4) Esterification Increases Bioavailability of Rosmarinic Acid and Its Potency to Inhibit Vascular Smooth Muscle Cell Proliferation
por: Blažević, Tina, et al.
Publicado: (2021)

Polyyne Hybrid Compounds from Notopterygium incisum with Peroxisome Proliferator-Activated Receptor Gamma Agonistic Effects
por: Liu, Xin, et al.
Publicado: (2014)

Resveratrol blocks Akt activation in angiotensin II- or EGF-stimulated vascular smooth muscle cells in a redox-independent manner
por: Schreiner, Cornelia E., et al.
Publicado: (2011)

Interference with platelet-derived growth factor-induced signalling in vascular smooth muscle cells by roscovitine
por: Sroka, Irene, et al.
Publicado: (2008)

Identification of Ostruthin from Peucedanum ostruthium Rhizomes as an Inhibitor of Vascular Smooth Muscle Cell Proliferation
por: Joa, Helge, et al.
Publicado: (2011)

Polyacetylenes from Notopterygium incisum–New Selective Partial Agonists of Peroxisome Proliferator-Activated Receptor-Gamma
por: Atanasov, Atanas G., et al.
Publicado: (2013)

Indirubin-3′-monoxime exerts a dual mode of inhibition towards leukotriene-mediated vascular smooth muscle cell migration
por: Blažević, Tina, et al.
Publicado: (2014)

The Dietary Constituent Falcarindiol Promotes Cholesterol Efflux from THP-1 Macrophages by Increasing ABCA1 Gene Transcription and Protein Stability
por: Wang, Limei, et al.
Publicado: (2017)

Benefits of Ginger and Its Constituent 6-Shogaol in Inhibiting Inflammatory Processes
por: Bischoff-Kont, Iris, et al.
Publicado: (2021)

Activated AMPK boosts the Nrf2/HO-1 signaling axis—A role for the unfolded protein response
por: Zimmermann, Kristin, et al.
Publicado: (2015)

Glycolytic Switch in Response to Betulinic Acid in Non-Cancer Cells
por: Heiss, Elke H., et al.
Publicado: (2014)

Indirubin and Indirubin Derivatives for Counteracting Proliferative Diseases
por: Blažević, Tina, et al.
Publicado: (2015)

The microRNAs Regulating Vascular Smooth Muscle Cell Proliferation: A Minireview
por: Wang, Dongdong, et al.
Publicado: (2019)

Erythrodiol, an Olive Oil Constituent, Increases the Half-Life of ABCA1 and Enhances Cholesterol Efflux from THP-1-Derived Macrophages
por: Wang, Limei, et al.
Publicado: (2017)

Cultured rat aortic vascular smooth muscle cells do not express a functional TRPV1
por: Blažević, Tina, et al.
Publicado: (2023)

Identification of Isosilybin A from Milk Thistle Seeds as an Agonist of Peroxisome Proliferator-Activated Receptor Gamma
por: Pferschy-Wenzig, Eva-Maria, et al.
Publicado: (2014)

Silymarin Constituents Enhance ABCA1 Expression in THP-1 Macrophages
por: Wang, Limei, et al.
Publicado: (2015)

Optimization of Extraction Conditions for the 6-Shogaol-rich Extract from Ginger (Zingiber officinale Roscoe)
por: Ok, Seon, et al.
Publicado: (2012)

Ascorbate stimulates endothelial nitric oxide synthase enzyme activity by rapid modulation of its phosphorylation status
por: Ladurner, Angela, et al.
Publicado: (2012)

NF-κB Inhibitors from Eurycoma longifolia
por: Tran, Thi Van Anh, et al.
Publicado: (2014)

Eurycomalactone Inhibits Expression of Endothelial Adhesion Molecules at a Post-Transcriptional Level
por: Malainer, Clemens, et al.
Publicado: (2017)

2-(2,4-dihydroxyphenyl)-5-(E)-propenylbenzofuran promotes endothelial nitric oxide synthase activity in human endothelial cells
por: Ladurner, Angela, et al.
Publicado: (2012)

6-Shogaol-Rich Extract from Ginger Up-Regulates the Antioxidant Defense Systems in Cells and Mice
por: Bak, Min-Ji, et al.
Publicado: (2012)

Screening of Vietnamese medicinal plants for NF-κB signaling inhibitors: Assessing the activity of flavonoids from the stem bark of Oroxylum indicum
por: Tran, Thi Van Anh, et al.
Publicado: (2015)

Drugs from nature targeting inflammation (DNTI): a successful Austrian interdisciplinary network project
por: Waltenberger, Birgit, et al.
Publicado: (2016)

Comparing the effects of microwave radiation on 6-gingerol and 6-shogaol from ginger rhizomes (Zingiber officinale Rosc)
por: Teng, Hui, et al.
Publicado: (2019)

Ginger Constituent 6-Shogaol Inhibits Inflammation- and Angiogenesis-Related Cell Functions in Primary Human Endothelial Cells
por: Bischoff-Kont, Iris, et al.
Publicado: (2022)

Ginger Constituent 6-Shogaol Attenuates Vincristine-Induced Activation of Mouse Gastroesophageal Vagal Afferent C-Fibers
por: Patil, Mayur J., et al.
Publicado: (2022)

Formation of 6-, 8- and 10-Shogaol in Ginger through Application of Different Drying Methods: Altered Antioxidant and Antimicrobial Activity
por: Ghasemzadeh, Ali, et al.
Publicado: (2018)

Pharmacokinetics and Tissue Distribution of Gingerols and Shogaols from Ginger (Zingiber officinale Rosc.) in Rats by UPLC–Q-Exactive–HRMS
por: Li, Ling-Ling, et al.
Publicado: (2019)

Protective Effects of 6-Shogaol, an Active Compound of Ginger, in a Murine Model of Cisplatin-Induced Acute Kidney Injury
por: Gwon, Mi-Gyeong, et al.
Publicado: (2021)

Bilirubin Decreases Macrophage Cholesterol Efflux and ATP‐Binding Cassette Transporter A1 Protein Expression
por: Wang, Dongdong, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_9vp6svsorrm5jbn0boqmkf63jp