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Synthesis of hybrid hydrazino peptides: protected vs unprotected chiral α-hydrazino acids
Peptidomimetics based on hydrazino derivatives of α-amino acids represent an important class of peptidic foldamers with promising biological activities, like protease inhibition and antimicrobial activity. However, the lack of straightforward method for the synthesis of optically pure hydrazino acid...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573739/ https://www.ncbi.nlm.nih.gov/pubmed/26405627 http://dx.doi.org/10.1186/s40064-015-1288-9 |