Foxa2 and Cdx2 cooperate with Nkx2-1 to inhibit lung adenocarcinoma metastasis

Despite the fact that the majority of lung cancer deaths are due to metastasis, the molecular mechanisms driving metastatic progression are poorly understood. Here, we present evidence that loss of Foxa2 and Cdx2 synergizes with loss of Nkx2-1 to fully activate the metastatic program. These three li...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Carman Man-Chung, Gocheva, Vasilena, Oudin, Madeleine J., Bhutkar, Arjun, Wang, Shi Yun, Date, Saya R., Ng, Sheng Rong, Whittaker, Charles A., Bronson, Roderick T., Snyder, Eric L., Gertler, Frank B., Jacks, Tyler
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573857/
https://www.ncbi.nlm.nih.gov/pubmed/26341558
http://dx.doi.org/10.1101/gad.267393.115

Ejemplares similares

Ejemplares similares