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Successful resolution of symmetrical peripheral gangrene after severe acute pancreatitis: a case report
INTRODUCTION: Symmetrical peripheral gangrene is an uncommon but devastating complication in critically ill patients, and it has a high mortality. It is seen in a wide variety of medical conditions, presenting as symmetrical gangrene of two or more extremities without large blood vessel obstruction....
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573942/ https://www.ncbi.nlm.nih.gov/pubmed/26376919 http://dx.doi.org/10.1186/s13256-015-0688-3 |
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author | Liao, Chen-Yi Huang, Shih-Chung Lin, Cheng-Hui Wang, Chih-Chiang Liu, Mei-Yu Ben, Ren-Jy Kuo, Wu-Hsien Lee, Ching-Chang |
author_facet | Liao, Chen-Yi Huang, Shih-Chung Lin, Cheng-Hui Wang, Chih-Chiang Liu, Mei-Yu Ben, Ren-Jy Kuo, Wu-Hsien Lee, Ching-Chang |
author_sort | Liao, Chen-Yi |
collection | PubMed |
description | INTRODUCTION: Symmetrical peripheral gangrene is an uncommon but devastating complication in critically ill patients, and it has a high mortality. It is seen in a wide variety of medical conditions, presenting as symmetrical gangrene of two or more extremities without large blood vessel obstruction. CASE PRESENTATION: We report a case of a 44-year-old Chinese man who was diagnosed with alcohol-related severe acute pancreatitis and presented with systemic inflammatory response syndrome and intractable vomiting. On the fourth day of admission, the patient developed cyanosis and gangrene of the fingers bilaterally. His cyanosis and gangrene did not resolve despite tapering of the vasopressor treatment. Gradually, his digital gangrene improved after administration of anti-platelet medication and pentoxifylline. CONCLUSIONS: To the best of our knowledge, this is the first case report of symmetrical peripheral gangrene occurring after acute pancreatitis with successful resolution. We highlight the importance of prompt and aggressive fluid resuscitation and consideration of multiple treatment options to prevent a hypovolemic state caused by acute pancreatitis. |
format | Online Article Text |
id | pubmed-4573942 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-45739422015-09-19 Successful resolution of symmetrical peripheral gangrene after severe acute pancreatitis: a case report Liao, Chen-Yi Huang, Shih-Chung Lin, Cheng-Hui Wang, Chih-Chiang Liu, Mei-Yu Ben, Ren-Jy Kuo, Wu-Hsien Lee, Ching-Chang J Med Case Rep Case Report INTRODUCTION: Symmetrical peripheral gangrene is an uncommon but devastating complication in critically ill patients, and it has a high mortality. It is seen in a wide variety of medical conditions, presenting as symmetrical gangrene of two or more extremities without large blood vessel obstruction. CASE PRESENTATION: We report a case of a 44-year-old Chinese man who was diagnosed with alcohol-related severe acute pancreatitis and presented with systemic inflammatory response syndrome and intractable vomiting. On the fourth day of admission, the patient developed cyanosis and gangrene of the fingers bilaterally. His cyanosis and gangrene did not resolve despite tapering of the vasopressor treatment. Gradually, his digital gangrene improved after administration of anti-platelet medication and pentoxifylline. CONCLUSIONS: To the best of our knowledge, this is the first case report of symmetrical peripheral gangrene occurring after acute pancreatitis with successful resolution. We highlight the importance of prompt and aggressive fluid resuscitation and consideration of multiple treatment options to prevent a hypovolemic state caused by acute pancreatitis. BioMed Central 2015-09-17 /pmc/articles/PMC4573942/ /pubmed/26376919 http://dx.doi.org/10.1186/s13256-015-0688-3 Text en © Liao et al. 2015 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Case Report Liao, Chen-Yi Huang, Shih-Chung Lin, Cheng-Hui Wang, Chih-Chiang Liu, Mei-Yu Ben, Ren-Jy Kuo, Wu-Hsien Lee, Ching-Chang Successful resolution of symmetrical peripheral gangrene after severe acute pancreatitis: a case report |
title | Successful resolution of symmetrical peripheral gangrene after severe acute pancreatitis: a case report |
title_full | Successful resolution of symmetrical peripheral gangrene after severe acute pancreatitis: a case report |
title_fullStr | Successful resolution of symmetrical peripheral gangrene after severe acute pancreatitis: a case report |
title_full_unstemmed | Successful resolution of symmetrical peripheral gangrene after severe acute pancreatitis: a case report |
title_short | Successful resolution of symmetrical peripheral gangrene after severe acute pancreatitis: a case report |
title_sort | successful resolution of symmetrical peripheral gangrene after severe acute pancreatitis: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573942/ https://www.ncbi.nlm.nih.gov/pubmed/26376919 http://dx.doi.org/10.1186/s13256-015-0688-3 |
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