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Mitochondrial Profiling of Acute Myeloid Leukemia in the Assessment of Response to Apoptosis Modulating Drugs

BH3 profiling measures the propensity of transformed cells to undergo intrinsic apoptosis and is determined by exposing cells to BH3-mimicking peptides. We hypothesized that basal levels of prosurvival BCL-2 family proteins may modulate the predictive power of BH3 profiling and termed it mitochondri...

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Detalles Bibliográficos
Autores principales:	Ishizawa, Jo, Kojima, Kensuke, McQueen, Teresa, Ruvolo, Vivian, Chachad, Dhruv, Nogueras-Gonzalez, Graciela M., Huang, Xuelin, Pierceall, William E., Dettman, E. J., Cardone, Michael H., Shacham, Sharon, Konopleva, Marina, Andreeff, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573975/ https://www.ncbi.nlm.nih.gov/pubmed/26375587 http://dx.doi.org/10.1371/journal.pone.0138377

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