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Targeting Mortalin by Embelin Causes Activation of Tumor Suppressor p53 and Deactivation of Metastatic Signaling in Human Breast Cancer Cells
Embelin, a natural quinone found in the fruits of Embelia ribes, is commonly used in Ayurvedic home medicine for a variety of therapeutic potentials including anti-inflammation, anti-fever, anti-bacteria and anti-cancer. Molecular mechanisms of these activities and cellular targets have not been cla...
Autores principales: | Nigam, Nupur, Grover, Abhinav, Goyal, Sukriti, Katiyar, Shashank P., Bhargava, Priyanshu, Wang, Pi-Chao, Sundar, Durai, Kaul, Sunil C., Wadhwa, Renu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574062/ https://www.ncbi.nlm.nih.gov/pubmed/26376435 http://dx.doi.org/10.1371/journal.pone.0138192 |
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