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NT-020 treatment reduces inflammation and augments Nrf-2 and Wnt signaling in aged rats
BACKGROUND: Aging is associated with a decline in stem cell proliferation that is thought to be a result of dysregulated signaling in the neurogenic niche. This results in a diminished and less efficient pool of progenitors. The Wnt pathway plays a key role in the proliferation and differentiation o...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574066/ https://www.ncbi.nlm.nih.gov/pubmed/26376629 http://dx.doi.org/10.1186/s12974-015-0395-4 |