Molecular Cloning and Functional Expression of the Equine K(+) Channel K(V)11.1 (Ether à Go-Go-Related/KCNH2 Gene) and the Regulatory Subunit KCNE2 from Equine Myocardium

The KCNH2 and KCNE2 genes encode the cardiac voltage-gated K(+) channel K(V)11.1 and its auxiliary β subunit KCNE2. K(V)11.1 is critical for repolarization of the cardiac action potential. In humans, mutations or drug therapy affecting the K(V)11.1 channel are associated with prolongation of the QT...

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Detalles Bibliográficos
Autores principales: Pedersen, Philip Juul, Thomsen, Kirsten Brolin, Olander, Emma Rie, Hauser, Frank, Tejada, Maria de los Angeles, Poulsen, Kristian Lundgaard, Grubb, Soren, Buhl, Rikke, Calloe, Kirstine, Klaerke, Dan Arne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574097/
https://www.ncbi.nlm.nih.gov/pubmed/26376488
http://dx.doi.org/10.1371/journal.pone.0138320

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