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A molecular modeling based screening for potential inhibitors to alpha hemolysin from Staphylococcus aureus

Staphylococcus aureus, a Gram-positive bacterium is pathogenic in nature. It is known that secreted toxins remain active after antibiotic treatment. The alpha hemolysin or alpha toxin damages cell membrane and induces apoptosis and degradation of DNA. The titer of alphahemolysin increases and causes...

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Detalles Bibliográficos
Autores principales: Rashidieh, Behnam, Etemadiafshar, Sarah, Memari, Golnaz, Mirzaeichegeni, Masoumeh, Yazdi, Shahrzad, Farsimadan, Fatemeh, Alizadeh, Soodabeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574119/
https://www.ncbi.nlm.nih.gov/pubmed/26420917
http://dx.doi.org/10.6026/97320630011373