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Linking altered central pain processing and genetic polymorphism to drug efficacy in chronic low back pain

BACKGROUND: Inability to predict the therapeutic effect of a drug in individual pain patients prolongs the process of drug and dose finding until satisfactory pharmacotherapy can be achieved. Many chronic pain conditions are associated with hypersensitivity of the nervous system or impaired endogeno...

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Detalles Bibliográficos
Autores principales: Siegenthaler, Andreas, Schliessbach, Jürg, Vuilleumier, Pascal H., Juni, Peter, Zeilhofer, Hanns U., Arendt-Nielsen, Lars, Curatolo, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574129/
https://www.ncbi.nlm.nih.gov/pubmed/26376691
http://dx.doi.org/10.1186/s40360-015-0023-z