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Linking altered central pain processing and genetic polymorphism to drug efficacy in chronic low back pain
BACKGROUND: Inability to predict the therapeutic effect of a drug in individual pain patients prolongs the process of drug and dose finding until satisfactory pharmacotherapy can be achieved. Many chronic pain conditions are associated with hypersensitivity of the nervous system or impaired endogeno...
Autores principales: | Siegenthaler, Andreas, Schliessbach, Jürg, Vuilleumier, Pascal H., Juni, Peter, Zeilhofer, Hanns U., Arendt-Nielsen, Lars, Curatolo, Michele |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574129/ https://www.ncbi.nlm.nih.gov/pubmed/26376691 http://dx.doi.org/10.1186/s40360-015-0023-z |
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