Inhibition of NOX2 reduces locomotor impairment, inflammation, and oxidative stress after spinal cord injury

BACKGROUND: Spinal cord injury (SCI) results in the activation of the NADPH oxidase (NOX) enzyme, inducing production of reactive oxygen species (ROS). We hypothesized that the NOX2 isoform plays an integral role in post-SCI inflammation and functional deficits. METHODS: Moderate spinal cord contusi...

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Detalles Bibliográficos
Autores principales: Khayrullina, Guzal, Bermudez, Sara, Byrnes, Kimberly R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574142/
https://www.ncbi.nlm.nih.gov/pubmed/26377802
http://dx.doi.org/10.1186/s12974-015-0391-8

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