The polarity protein Scrib mediates epidermal development and exerts a tumor suppressive function during skin carcinogenesis

BACKGROUND: The establishment and maintenance of polarity is vital for embryonic development and loss of polarity is a frequent characteristic of epithelial cancers, however the underlying molecular mechanisms remain unclear. Here, we identify a novel role for the polarity protein Scrib as a mediato...

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Detalles Bibliográficos
Autores principales: Pearson, Helen B., McGlinn, Edwina, Phesse, Toby J., Schlüter, Holger, Srikumar, Anuratha, Gödde, Nathan J., Woelwer, Christina B., Ryan, Andrew, Phillips, Wayne A., Ernst, Matthias, Kaur, Pritinder, Humbert, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574215/
https://www.ncbi.nlm.nih.gov/pubmed/26376988
http://dx.doi.org/10.1186/s12943-015-0440-z

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