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Activation of Src-dependent Smad3 signaling mediates the neutrophilic inflammation and oxidative stress in hyperoxia-augmented ventilator-induced lung injury

BACKGROUND: Mechanical ventilation and concomitant administration of hyperoxia in patients with acute respiratory distress syndrome can damage the alveolar epithelial and capillary endothelial barrier by producing inflammatory cytokines and reactive oxygen species. The Src tyrosine kinase and Smad3...

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Detalles Bibliográficos
Autores principales:	Li, Li-Fu, Lee, Chung-Shu, Liu, Yung-Yang, Chang, Chih-Hao, Lin, Chang-Wei, Chiu, Li-Chung, Kao, Kuo-Chin, Chen, Ning-Hung, Yang, Cheng-Ta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574227/ https://www.ncbi.nlm.nih.gov/pubmed/26377087 http://dx.doi.org/10.1186/s12931-015-0275-6

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