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Freedom and Responsibility in Synthetic Genomics: The Synthetic Yeast Project

First introduced in 2011, the Synthetic Yeast Genome (Sc2.0) Project is a large international synthetic genomics project that will culminate in the first eukaryotic cell (Saccharomyces cerevisiae) with a fully synthetic genome. With collaborators from across the globe and from a range of institution...

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Detalles Bibliográficos
Autores principales: Sliva, Anna, Yang, Huanming, Boeke, Jef D., Mathews, Debra J. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574254/
https://www.ncbi.nlm.nih.gov/pubmed/26272997
http://dx.doi.org/10.1534/genetics.115.176370
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author Sliva, Anna
Yang, Huanming
Boeke, Jef D.
Mathews, Debra J. H.
author_facet Sliva, Anna
Yang, Huanming
Boeke, Jef D.
Mathews, Debra J. H.
author_sort Sliva, Anna
collection PubMed
description First introduced in 2011, the Synthetic Yeast Genome (Sc2.0) Project is a large international synthetic genomics project that will culminate in the first eukaryotic cell (Saccharomyces cerevisiae) with a fully synthetic genome. With collaborators from across the globe and from a range of institutions spanning from do-it-yourself biology (DIYbio) to commercial enterprises, it is important that all scientists working on this project are cognizant of the ethical and policy issues associated with this field of research and operate under a common set of principles. In this commentary, we survey the current ethics and regulatory landscape of synthetic biology and present the Sc2.0 Statement of Ethics and Governance to which all members of the project adhere. This statement focuses on four aspects of the Sc2.0 Project: societal benefit, intellectual property, safety, and self-governance. We propose that such project-level agreements are an important, valuable, and flexible model of self-regulation for similar global, large-scale synthetic biology projects in order to maximize the benefits and minimize potential harms.
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spelling pubmed-45742542015-09-21 Freedom and Responsibility in Synthetic Genomics: The Synthetic Yeast Project Sliva, Anna Yang, Huanming Boeke, Jef D. Mathews, Debra J. H. Genetics Commentary First introduced in 2011, the Synthetic Yeast Genome (Sc2.0) Project is a large international synthetic genomics project that will culminate in the first eukaryotic cell (Saccharomyces cerevisiae) with a fully synthetic genome. With collaborators from across the globe and from a range of institutions spanning from do-it-yourself biology (DIYbio) to commercial enterprises, it is important that all scientists working on this project are cognizant of the ethical and policy issues associated with this field of research and operate under a common set of principles. In this commentary, we survey the current ethics and regulatory landscape of synthetic biology and present the Sc2.0 Statement of Ethics and Governance to which all members of the project adhere. This statement focuses on four aspects of the Sc2.0 Project: societal benefit, intellectual property, safety, and self-governance. We propose that such project-level agreements are an important, valuable, and flexible model of self-regulation for similar global, large-scale synthetic biology projects in order to maximize the benefits and minimize potential harms. Genetics Society of America 2015-08 2015-08-10 /pmc/articles/PMC4574254/ /pubmed/26272997 http://dx.doi.org/10.1534/genetics.115.176370 Text en Copyright © 2015 by the Genetics Society of America Available freely online through the author-supported open access option.
spellingShingle Commentary
Sliva, Anna
Yang, Huanming
Boeke, Jef D.
Mathews, Debra J. H.
Freedom and Responsibility in Synthetic Genomics: The Synthetic Yeast Project
title Freedom and Responsibility in Synthetic Genomics: The Synthetic Yeast Project
title_full Freedom and Responsibility in Synthetic Genomics: The Synthetic Yeast Project
title_fullStr Freedom and Responsibility in Synthetic Genomics: The Synthetic Yeast Project
title_full_unstemmed Freedom and Responsibility in Synthetic Genomics: The Synthetic Yeast Project
title_short Freedom and Responsibility in Synthetic Genomics: The Synthetic Yeast Project
title_sort freedom and responsibility in synthetic genomics: the synthetic yeast project
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574254/
https://www.ncbi.nlm.nih.gov/pubmed/26272997
http://dx.doi.org/10.1534/genetics.115.176370
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