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Genetic variations in genes of metabolic enzymes predict postoperational prognosis of patients with colorectal cancer

BACKGROUND: Genetic alterations in tricarboxylic acid (TCA) cycle metabolic enzymes were recently linked to various cancers. However, the associations of single nucleotide polymorphisms (SNPs) in genes of these enzymes have not been well studied. METHODS: We genotyped 16 SNPs from 7 genes encoding T...

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Detalles Bibliográficos
Autores principales: Dong, Guanglong, He, Xianli, Chen, Yibing, Cao, Haiyan, Wang, Jiaojiao, Liu, Xiaonan, Wang, Shukui, Wan, Shaogui, Xing, Jinliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574264/
https://www.ncbi.nlm.nih.gov/pubmed/26377099
http://dx.doi.org/10.1186/s12943-015-0442-x