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Evidence for lung epithelial stem cell niches

Recent studies have identified epithelial stem and progenitor cell populations of the lung. We are just beginning to understand the mechanisms that regulate their homeostatic, regenerative and maladaptive behaviors. Here, we discuss evidence of regulatory niches for epithelial stem cells of the lung...

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Detalles Bibliográficos
Autores principales: Donne, Matt L., Lechner, Andrew J., Rock, Jason R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574358/
https://www.ncbi.nlm.nih.gov/pubmed/26376663
http://dx.doi.org/10.1186/s12861-015-0082-9
Descripción
Sumario:Recent studies have identified epithelial stem and progenitor cell populations of the lung. We are just beginning to understand the mechanisms that regulate their homeostatic, regenerative and maladaptive behaviors. Here, we discuss evidence of regulatory niches for epithelial stem cells of the lung.