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Gene repositioning within the cell nucleus is not random and is determined by its genomic neighborhood
BACKGROUND: Heterochromatin has been reported to be a major silencing compartment during development and differentiation. Prominent heterochromatin compartments are located at the nuclear periphery and inside the nucleus (e.g., pericentric heterochromatin). Whether the position of a gene in relation...
Autores principales: | Jost, K. Laurence, Bertulat, Bianca, Rapp, Alexander, Brero, Alessandro, Hardt, Tanja, Domaing, Petra, Gösele, Claudia, Schulz, Herbert, Hübner, Norbert, Cardoso, M. Cristina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574441/ https://www.ncbi.nlm.nih.gov/pubmed/26388944 http://dx.doi.org/10.1186/s13072-015-0025-5 |
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