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PI3Kδ Regulates the Magnitude of CD8(+) T Cell Responses after Challenge with Listeria monocytogenes

PI3Ks regulate diverse immune cell functions by transmitting intracellular signals from Ag, costimulatory receptors, and cytokine receptors to control cell division, differentiation, survival, and migration. In this study, we report the effect of inhibiting the p110δ subunit of PI3Kδ on CD8(+) T cel...

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Detalles Bibliográficos
Autores principales:	Pearce, Verity Q., Bouabe, Hicham, MacQueen, Amy R., Carbonaro, Valentina, Okkenhaug, Klaus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AAI 2015
Materias:	Infectious Disease and Host Response
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574522/ https://www.ncbi.nlm.nih.gov/pubmed/26311905 http://dx.doi.org/10.4049/jimmunol.1501227

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