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Suppression of NF-κB and NF-κB-Regulated Gene Expression by Apigenin through IκBα and IKK Pathway in TRAMP Mice

Aberrant Nuclear Factor-κappaB (NF-κB) activation due to rapid IκBα turnover and high basal IκBα kinase (IKK) activity has been frequently observed in prostate cancer. Apigenin, a naturally occurring plant flavone, exhibits anti-proliferative, anti-inflammatory and anti-carcinogenic activities by in...

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Detalles Bibliográficos
Autores principales:	Shukla, Sanjeev, Shankar, Eswar, Fu, Pingfu, MacLennan, Gregory T., Gupta, Sanjay
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574560/ https://www.ncbi.nlm.nih.gov/pubmed/26379052 http://dx.doi.org/10.1371/journal.pone.0138710

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