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Adolescents in a residential school for behavior disorders have an elevated mortality risk in young adulthood

BACKGROUND: Conduct problems during adolescence are associated with an elevated mortality risk. This study investigated the mortality rate, causes of death, and changes over time in a Finnish residential school (RS) population. METHODS: All adolescents (N = 885, M/F = 594/291, age mean 15.2 years at...

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Autores principales: Manninen, Marko, Pankakoski, Maiju, Gissler, Mika, Suvisaari, Jaana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574605/
https://www.ncbi.nlm.nih.gov/pubmed/26388934
http://dx.doi.org/10.1186/s13034-015-0078-z
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author Manninen, Marko
Pankakoski, Maiju
Gissler, Mika
Suvisaari, Jaana
author_facet Manninen, Marko
Pankakoski, Maiju
Gissler, Mika
Suvisaari, Jaana
author_sort Manninen, Marko
collection PubMed
description BACKGROUND: Conduct problems during adolescence are associated with an elevated mortality risk. This study investigated the mortality rate, causes of death, and changes over time in a Finnish residential school (RS) population. METHODS: All adolescents (N = 885, M/F = 594/291, age mean 15.2 years at baseline) residing in the RS system in 1991, 1996, 2001, and 2006 and matched controls were included in a register-based study with a follow-up time of up to 22 years. RESULTS: The all-cause mortality rate for people with an RS background was 6.7 % compared to 1.0 % in the controls (Hazard Ratio HR = 6.95, 95 % 4.66–10.37, p < 0.001). 8.1 % of the RS boys had died compared to 2.2 % of the girls (HR = 2.2, p = 0.02). The HR for substance-related death was 24.31 (95 % CI 9.3–65.53, P < 0.001), for suicide 7.23 (95 % CI 3.24–16.11, P < 0.001) and for other external causes 5.45 (95 % CI 2.41–12.36, P < 0.001) compared to controls. Mortality peaked among RS boys at approximately 25 years, whereas for girls it peaked after 30 years. CONCLUSIONS: Adolescents with severe disruptive behavior problems have a seven-fold risk for premature adult-age death compared to matched controls. The most common causes for death were avoidable, substance-related followed by suicide. Effective treatment of mental and substance use related problems during and after the placement is needed to reduce mortality.
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spelling pubmed-45746052015-09-19 Adolescents in a residential school for behavior disorders have an elevated mortality risk in young adulthood Manninen, Marko Pankakoski, Maiju Gissler, Mika Suvisaari, Jaana Child Adolesc Psychiatry Ment Health Research Article BACKGROUND: Conduct problems during adolescence are associated with an elevated mortality risk. This study investigated the mortality rate, causes of death, and changes over time in a Finnish residential school (RS) population. METHODS: All adolescents (N = 885, M/F = 594/291, age mean 15.2 years at baseline) residing in the RS system in 1991, 1996, 2001, and 2006 and matched controls were included in a register-based study with a follow-up time of up to 22 years. RESULTS: The all-cause mortality rate for people with an RS background was 6.7 % compared to 1.0 % in the controls (Hazard Ratio HR = 6.95, 95 % 4.66–10.37, p < 0.001). 8.1 % of the RS boys had died compared to 2.2 % of the girls (HR = 2.2, p = 0.02). The HR for substance-related death was 24.31 (95 % CI 9.3–65.53, P < 0.001), for suicide 7.23 (95 % CI 3.24–16.11, P < 0.001) and for other external causes 5.45 (95 % CI 2.41–12.36, P < 0.001) compared to controls. Mortality peaked among RS boys at approximately 25 years, whereas for girls it peaked after 30 years. CONCLUSIONS: Adolescents with severe disruptive behavior problems have a seven-fold risk for premature adult-age death compared to matched controls. The most common causes for death were avoidable, substance-related followed by suicide. Effective treatment of mental and substance use related problems during and after the placement is needed to reduce mortality. BioMed Central 2015-09-02 /pmc/articles/PMC4574605/ /pubmed/26388934 http://dx.doi.org/10.1186/s13034-015-0078-z Text en © Manninen et al. 2015 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Manninen, Marko
Pankakoski, Maiju
Gissler, Mika
Suvisaari, Jaana
Adolescents in a residential school for behavior disorders have an elevated mortality risk in young adulthood
title Adolescents in a residential school for behavior disorders have an elevated mortality risk in young adulthood
title_full Adolescents in a residential school for behavior disorders have an elevated mortality risk in young adulthood
title_fullStr Adolescents in a residential school for behavior disorders have an elevated mortality risk in young adulthood
title_full_unstemmed Adolescents in a residential school for behavior disorders have an elevated mortality risk in young adulthood
title_short Adolescents in a residential school for behavior disorders have an elevated mortality risk in young adulthood
title_sort adolescents in a residential school for behavior disorders have an elevated mortality risk in young adulthood
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574605/
https://www.ncbi.nlm.nih.gov/pubmed/26388934
http://dx.doi.org/10.1186/s13034-015-0078-z
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