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A glyS T-box riboswitch with species-specific structural features responding to both proteinogenic and nonproteinogenic tRNA(Gly) isoacceptors

In Staphylococcus aureus, a T-box riboswitch exists upstream of the glyS gene to regulate transcription of the sole glycyl-tRNA synthetase, which aminoacylates five tRNA(Gly) isoacceptors bearing GCC or UCC anticodons. Subsequently, the glycylated tRNAs serve as substrates for decoding glycine codon...

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Detalles Bibliográficos
Autores principales: Apostolidi, Maria, Saad, Nizar Y., Drainas, Denis, Pournaras, Spyros, Becker, Hubert D., Stathopoulos, Constantinos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574755/
https://www.ncbi.nlm.nih.gov/pubmed/26276802
http://dx.doi.org/10.1261/rna.052712.115