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Poly(U) RNA-templated synthesis of AppA
Simple nucleotide templating activities are of interest as potential primordial reactions. Here we describe the acceleration of 5′-5′ AppA synthesis by 3′-5′ poly(U) under normal solution conditions. This reaction is apparently templated via complementary U:A base-pairing, despite the involvement of...
Autores principales: | Puthenvedu, Deepa, Janas, Teresa, Majerfeld, Irene, Illangasekare, Mali, Yarus, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574757/ https://www.ncbi.nlm.nih.gov/pubmed/26272215 http://dx.doi.org/10.1261/rna.052696.115 |
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