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Effect of Intramuscular Protons, Lactate, and ATP on Muscle Hyperalgesia in Rats

Chronic muscle pain is a significant health problem leading to disability[1]. Muscle fatigue can exacerbate muscle pain. Metabolites, including ATP, lactate, and protons, are released during fatiguing exercise and produce pain in humans. These substances directly activate purinergic (P2X) and acid s...

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Detalles Bibliográficos
Autores principales: Gregory, Nicholas S., Whitley, Phillip E., Sluka, Kathleen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574767/
https://www.ncbi.nlm.nih.gov/pubmed/26378796
http://dx.doi.org/10.1371/journal.pone.0138576