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Effect of Intramuscular Protons, Lactate, and ATP on Muscle Hyperalgesia in Rats
Chronic muscle pain is a significant health problem leading to disability[1]. Muscle fatigue can exacerbate muscle pain. Metabolites, including ATP, lactate, and protons, are released during fatiguing exercise and produce pain in humans. These substances directly activate purinergic (P2X) and acid s...
Autores principales: | Gregory, Nicholas S., Whitley, Phillip E., Sluka, Kathleen A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574767/ https://www.ncbi.nlm.nih.gov/pubmed/26378796 http://dx.doi.org/10.1371/journal.pone.0138576 |
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