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A Method to Constrain Genome-Scale Models with (13)C Labeling Data

Current limitations in quantitatively predicting biological behavior hinder our efforts to engineer biological systems to produce biofuels and other desired chemicals. Here, we present a new method for calculating metabolic fluxes, key targets in metabolic engineering, that incorporates data from (1...

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Detalles Bibliográficos
Autores principales:	García Martín, Héctor, Kumar, Vinay Satish, Weaver, Daniel, Ghosh, Amit, Chubukov, Victor, Mukhopadhyay, Aindrila, Arkin, Adam, Keasling, Jay D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574858/ https://www.ncbi.nlm.nih.gov/pubmed/26379153 http://dx.doi.org/10.1371/journal.pcbi.1004363

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