Lithium Decreases Glial Fibrillary Acidic Protein in a Mouse Model of Alexander Disease

Alexander disease is a fatal neurodegenerative disease caused by mutations in the astrocyte intermediate filament glial fibrillary acidic protein (GFAP). The disease is characterized by elevated levels of GFAP and the formation of protein aggregates, known as Rosenthal fibers, within astrocytes. Lit...

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Detalles Bibliográficos
Autores principales: LaPash Daniels, Christine M., Paffenroth, Elizabeth, Austin, Elizabeth V., Glebov, Konstantin, Lewis, Diana, Walter, Jochen, Messing, Albee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574949/
https://www.ncbi.nlm.nih.gov/pubmed/26378915
http://dx.doi.org/10.1371/journal.pone.0138132

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