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Myoepithelial hamartoma as a solitary mass in the pancreatic parenchyma: the first case report

Solid hamartoma of the pancreas is very rare, and only 3 cases have been reported thus far. A patient underwent pancreaticoduodenectomy due to a mass in the head of the pancreas which was suspected to be a borderline malignant tumor, but the histologic diagnosis turned out to be myoepithelial hamart...

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Autores principales: Kwon, Wooil, Kim, Sun-Whe, Lee, Kyoung Bun, Jang, Jin-Young, Park, Jae Woo, Han, In Woong, Kang, Mee Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Association of Hepato-Biliary-Pancreatic Surgery 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574988/
https://www.ncbi.nlm.nih.gov/pubmed/26388912
http://dx.doi.org/10.14701/kjhbps.2012.16.2.80
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author Kwon, Wooil
Kim, Sun-Whe
Lee, Kyoung Bun
Jang, Jin-Young
Park, Jae Woo
Han, In Woong
Kang, Mee Joo
author_facet Kwon, Wooil
Kim, Sun-Whe
Lee, Kyoung Bun
Jang, Jin-Young
Park, Jae Woo
Han, In Woong
Kang, Mee Joo
author_sort Kwon, Wooil
collection PubMed
description Solid hamartoma of the pancreas is very rare, and only 3 cases have been reported thus far. A patient underwent pancreaticoduodenectomy due to a mass in the head of the pancreas which was suspected to be a borderline malignant tumor, but the histologic diagnosis turned out to be myoepithelial hamartoma (MEH) or adenomyoma. It was characterized by benign duct and glandular structures surrounded by proliferating smooth muscle, and acinus formation was not observed. Immunohistochemical stain for smooth muscle actin (SMA) was positive in spindle cells, and CD34 was negative, differentiating it from the three previously reported cases of solid hamartoma of the pancreas. MEH is an entity that is on the same spectrum as heterotopic pancreas. MEH is rare and has usually been reported in the gastrointestinal tract. To the best of our knowledge, MEH has never been reported in the pancreas. Therefore we report the world's first documented case of MEH of the pancreas.
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spelling pubmed-45749882015-09-18 Myoepithelial hamartoma as a solitary mass in the pancreatic parenchyma: the first case report Kwon, Wooil Kim, Sun-Whe Lee, Kyoung Bun Jang, Jin-Young Park, Jae Woo Han, In Woong Kang, Mee Joo Korean J Hepatobiliary Pancreat Surg Case Report Solid hamartoma of the pancreas is very rare, and only 3 cases have been reported thus far. A patient underwent pancreaticoduodenectomy due to a mass in the head of the pancreas which was suspected to be a borderline malignant tumor, but the histologic diagnosis turned out to be myoepithelial hamartoma (MEH) or adenomyoma. It was characterized by benign duct and glandular structures surrounded by proliferating smooth muscle, and acinus formation was not observed. Immunohistochemical stain for smooth muscle actin (SMA) was positive in spindle cells, and CD34 was negative, differentiating it from the three previously reported cases of solid hamartoma of the pancreas. MEH is an entity that is on the same spectrum as heterotopic pancreas. MEH is rare and has usually been reported in the gastrointestinal tract. To the best of our knowledge, MEH has never been reported in the pancreas. Therefore we report the world's first documented case of MEH of the pancreas. Korean Association of Hepato-Biliary-Pancreatic Surgery 2012-05 2012-05-31 /pmc/articles/PMC4574988/ /pubmed/26388912 http://dx.doi.org/10.14701/kjhbps.2012.16.2.80 Text en Copyright © 2012 by The Korean Association of Hepato-Biliary-Pancreatic Surgery http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Kwon, Wooil
Kim, Sun-Whe
Lee, Kyoung Bun
Jang, Jin-Young
Park, Jae Woo
Han, In Woong
Kang, Mee Joo
Myoepithelial hamartoma as a solitary mass in the pancreatic parenchyma: the first case report
title Myoepithelial hamartoma as a solitary mass in the pancreatic parenchyma: the first case report
title_full Myoepithelial hamartoma as a solitary mass in the pancreatic parenchyma: the first case report
title_fullStr Myoepithelial hamartoma as a solitary mass in the pancreatic parenchyma: the first case report
title_full_unstemmed Myoepithelial hamartoma as a solitary mass in the pancreatic parenchyma: the first case report
title_short Myoepithelial hamartoma as a solitary mass in the pancreatic parenchyma: the first case report
title_sort myoepithelial hamartoma as a solitary mass in the pancreatic parenchyma: the first case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574988/
https://www.ncbi.nlm.nih.gov/pubmed/26388912
http://dx.doi.org/10.14701/kjhbps.2012.16.2.80
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