A Mitochondrion-Targeted Antioxidant Ameliorates Isoflurane-Induced Cognitive Deficits in Aging Mice

Isoflurane possesses neurotoxicity and can induce cognitive deficits, particularly in aging mammals. Mitochondrial reactive oxygen species (mtROS) have been linked to the early pathogenesis of this disorder. However, the role of mtROS remains to be evaluated due to a lack of targeted method to treat...

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Detalles Bibliográficos
Autores principales: Wu, Jing, Li, Huihui, Sun, Xiaoru, Zhang, Hui, Hao, Shuangying, Ji, Muhuo, Yang, Jianjun, Li, Kuanyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4575031/
https://www.ncbi.nlm.nih.gov/pubmed/26379247
http://dx.doi.org/10.1371/journal.pone.0138256

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4575031/
https://www.ncbi.nlm.nih.gov/pubmed/26379247
http://dx.doi.org/10.1371/journal.pone.0138256

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