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AS-703026 Inhibits LPS-Induced TNFα Production through MEK/ERK Dependent and Independent Mechanisms

Chronic obstructive pulmonary disease (COPD) is characterized by intense lung infiltrations of immune cells (macrophages and monocytes). Lipopolysaccharide (LPS) activates macrophages/monocytes, leading to production of tumor necrosis factor α (TNFα) and other cytokines, which cause subsequent lung...

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Detalles Bibliográficos
Autores principales:	Li, Ping, Wu, Yonghong, Li, Manxiang, Qiu, Xiaojuan, Bai, Xiaoyan, Zhao, Xiaojing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4575053/ https://www.ncbi.nlm.nih.gov/pubmed/26381508 http://dx.doi.org/10.1371/journal.pone.0137107

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