Integrating mRNA and miRNA Weighted Gene Co-Expression Networks with eQTLs in the Nucleus Accumbens of Subjects with Alcohol Dependence

Alcohol consumption is known to lead to gene expression changes in the brain. After performing weighted gene co-expression network analyses (WGCNA) on genome-wide mRNA and microRNA (miRNA) expression in Nucleus Accumbens (NAc) of subjects with alcohol dependence (AD; N = 18) and of matched controls...

Descripción completa

Detalles Bibliográficos
Autores principales: Mamdani, Mohammed, Williamson, Vernell, McMichael, Gowon O., Blevins, Tana, Aliev, Fazil, Adkins, Amy, Hack, Laura, Bigdeli, Tim, D. van der Vaart, Andrew, Web, Bradley Todd, Bacanu, Silviu-Alin, Kalsi, Gursharan, Kendler, Kenneth S., Miles, Michael F., Dick, Danielle, Riley, Brien P., Dumur, Catherine, Vladimirov, Vladimir I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4575063/
https://www.ncbi.nlm.nih.gov/pubmed/26381263
http://dx.doi.org/10.1371/journal.pone.0137671

Ejemplares similares

Ejemplares similares