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Phosphoenolpyruvate Carboxykinase, a Key Enzyme That Controls Blood Glucose, Is a Target of Retinoic Acid Receptor-Related Orphan Receptor α
Phosphoenolpyruvate carboxykinase (PEPCK) catalyzes a committed and rate-limiting step in hepatic gluconeogenesis, and its activity is tightly regulated to maintain blood glucose levels within normal limits. PEPCK activity is primarily regulated through hormonal control of gene transcription. Transc...
Autores principales: | Matsuoka, Hiroshi, Shima, Akiho, Kuramoto, Daisuke, Kikumoto, Daisuke, Matsui, Takashi, Michihara, Akihiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4575163/ https://www.ncbi.nlm.nih.gov/pubmed/26383638 http://dx.doi.org/10.1371/journal.pone.0137955 |
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