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Mycobacterium tuberculosis Is Resistant to Isoniazid at a Slow Growth Rate by Single Nucleotide Polymorphisms in katG Codon Ser(315)

An important aim for improving TB treatment is to shorten the period of antibiotic therapy without increasing relapse rates or encouraging the development of antibiotic-resistant strains. In any M. tuberculosis population there is a proportion of bacteria that are drug-tolerant; this might be becaus...

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Detalles Bibliográficos
Autores principales:	Jeeves, Rose E., Marriott, Alice A. N., Pullan, Steven T., Hatch, Kim A., Allnutt, Jon C., Freire-Martin, Irene, Hendon-Dunn, Charlotte L., Watson, Robert, Witney, Adam A., Tyler, Richard H., Arnold, Catherine, Marsh, Philip D., McHugh, Timothy D., Bacon, Joanna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4575197/ https://www.ncbi.nlm.nih.gov/pubmed/26382066 http://dx.doi.org/10.1371/journal.pone.0138253

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