Regulation of the Flt3 Gene in Haematopoietic Stem and Early Progenitor Cells

The MYB transcription factor plays critical roles in normal and malignant haematopoiesis. We previously showed that MYB was a direct activator of FLT3 expression within the context of acute myeloid leukaemia. During normal haematopoiesis, increasing levels of FLT3 expression determine a strict hiera...

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Detalles Bibliográficos
Autores principales: Volpe, Giacomo, Clarke, Mary, Garcìa, Paloma, Walton, David Scott, Vegiopoulos, Alexandros, Del Pozzo, Walter, O’Neill, Laura Patricia, Frampton, Jonathan, Dumon, Stéphanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4575200/
https://www.ncbi.nlm.nih.gov/pubmed/26382271
http://dx.doi.org/10.1371/journal.pone.0138257

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